Can cephalospore injure a kidney?Worse than you think!

Since our head is large, we call it "cephalospora."The cephalosporin is useful in the metabolites of the cephalospora, so we grabbed the cephalosporins and put in more than 60 cephalosporins in the market.

It's known that antibiotics can harm the kidneys, and the cephalospora family is a very large group of antibiotics.So are all the cephalospores injured?Now I'm going to take stock of the cephalospores.

First-generation cephalospore

Representative drugs: cefalotin (cephradine) 1, cephalosporins thiamethoxam organism pioneer (2), and physicochemical benzyl pioneer (4), cefazolin (pioneer) 5, cephalosporins pull pioneer (6), hydroxyl ammonia benzyl cephalosporin.

Nephrotoxicity: larger.

Generation cephalosporin may cause renal tubular necrosis, accelerate the process of deterioration of kidney disease, kidney disease patients is not recommended to use, it is mainly used for resistant s. aureus bacteria infection, and respiratory tract, urinary tract infections caused by sensitive bacteria.

Second-generation cephalospore

Representative drugs: meng cephalosporin cefepime (hydroxyl), cefuroxime sodium, cefuroxime ester, cefaclor, cephalosporins for Ann, cefmetazole, cefoxitin, cefazolin propylene, cefonicid, leite cephalosporin.

Nephrotoxicity: smaller than the previous generation.

It is mainly used for respiratory, biliary tract and urinary tract infection caused by sensitive bacteria.Cefuroxime (xilixin, lifu, fu yue xin, ankxin, blessing letter) is effective for respiratory, urinary system and other infections.

If kidney disease patients must use the second generation of cephalospores, it is better to reduce the dose and prolong the interval.

Note: combined with diuretics can aggravate kidney failure.

Tertiary cephalospore

Representative drugs: cefotaxime sodium, cefoperazone, he totally cephalosporin, ceftriaxone, cefazolin oxime, cephalosporins oxime, horse amine, cefotetan cephalosporin cefepime, cefixime, mooring oxime esters, cephalosporins he qin beauty ester, cephalosporins, cephalosporins thiamethoxam teng, cephalosporins, cefepime (cephalosporin, lanai, oxygen cephalosporin cefepime, cephalosporins cloth material, mino, rosie cephalosporin.

Nephrotoxicity: no nephrotoxicity.

Major infections caused by sensitive bacteria such as urinary tract, pneumonia, meningitis, sepsis and pseudomonas aeruginosa infection.Ceftidine is the most powerful antibiotic currently used for pseudomonas aeruginosa.

The third generation of cephalosporins is now serious and worrying.

Fourth-generation cephalospore

Representative drugs: cephalopime, cefepime, cefazole.

Nephrotoxicity: no.

The fourth generation of cephalospora was expanded to be used mainly for refractory infections.

In general, one or two cephalosporins are not suitable for patients with nephropathy due to renal toxicity.Three generations of cephalospore can be used in patients with kidney disease.

Final warning: eat cephalospora, or you will have acetaldehyde poisoning: respiratory inhibition, acute heart failure, myocardial infarction.

In particular, three generations of cephalospore and alcohol are encountered in cardiovascular patients.