NGAL

Function of NGAL test: NGAL;neutrpphil geatinaseassociated lipocalin, it is a new member in lipid carrier protein family, it is a sign of earlier kidney damage founded in recent years. When the acute kidney function damage, blood and urine NGAL concentration will go up, it can go up to tens and hundreds times than critical value in 2 hours. Compared with traditional index of serum creatinine and urinary enzymes,It can find renal damage earlier. In chronic kidney disease patients, NGAL level in serum blood and glomerular filtration rate is negative correlation. Compared with serum creatinine, NGAL can reflect the level of glomerular filtration rate. It is a biological indicator with features as sensitive, no wound and high specificity for chronic kidney disease early found, early treatment. For example, IgA nephropathy is the most common glomerular nephritis with featured as primary glomerular injury with tubular interstitial change, its tubule interstitial damage effects the disease development. NGAL can reflect on kidney tubule interstitial damage earlier in clinical. In lupus nephropathy patients, NGAL is better than anti-dsDNA on antibody titer in diagnosis indexes. It is an reversible predictive factor for lupus nephropathy activity. Chronic tubules interstitial nephritis caused by medicine damage, urine NGAL is better than mAlb，α1-MG and so on. It can reflect on kidney function damage degree. In Autosomal dominant polycystic kidney disease, checking up urine NGAL can assess kidney lesion degree. In the 2 style diabetic nephropathy patients, serum blood and urine NGAL level go up obviously, and they are sensitive to disease development, which is good to assess diabetic nephropathy patients kidney function. NGAL is also a better curative effects index of kidney disease, it can reflect kidney disease’s clinical curative effects.

Our advantage: earlier NGAL test adopt to ELISA, manufacture operation influence is more, it is not adapt to test of amounts samples. Beijing Tongshantang Hospital of Chinese Medicine in early 2012, pioneered in the United States at home and abroad abbott production Architecti1000SR full automatic immune NGAL urine analyzer using chemiluminescence immune analysis, has the automatic degree is high, easy to return, the specimens were not need manual pretreatment process, the required samples quantity is little and can batch determination, more important is through a large number of sample check results confirmed its determination in high speed accurately.