The four characteristics of Nephrotic syndrome’s clinic manifestation

The patients of nephrotic syndrome have four characteristics in clinic manifestations. A large amount of proteinuria, edema, hypoalbuminemia, hyperlipidemia. The below, I introduce specifically the nephrotic syndromn’clinic manifestations to you.


1. A large amount of proteinuria
The main component is proteinuria, including other plasma protein component. Patients will have lipid urine with proteinauria more than 3.5 grams per day. When the glomerular filtration rate falls and the proteinauri reduces; the heavily hypoalbuminemia, the excretion quantity of urine protein can increase and the high protein diet makes the urine protein excretion increase.

2. edema
The most notable sympotoms of patients is increasing gradually anacarca. initial morning eyelid, facial, ankle edema, gradual development as the illness, edema can be spread to the whole body, and pleural effusion, ascites, pericardial effusion, mediastinal effusion, scrotal edema or labia, and it also can appear pulmonary edema.

3. Hypoalbuminemia
Hypoalbuminemia refers to that patients with serum albumin below 30 grams per liter, when liver albumin in patients with compensatory effect is not enough to compensate for the loss of urine protein quantity, will appear hypoalbuminemia.

4. Hyperlipidemia
Hyperlipidemia is associated with low serum albumin. The patients can appear lipid in urine, urine having the double refraction fat body, for it contains cholesterol or fat body tube type of epithelial cells.a

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